Mahmoud Reza Ashrafi
Professor of Pediatric Neurology , Children’s Medical Center , Tehran University of Medical Sciences
Benign childhood focal seizures and epileptic syndromes are one of the most common seizure disorders of children and affect 25% of cases with nonfebrile seizures of this age group .
The three most common and recognized syndromes of idiopathic childhood focal epilepsies are
- benign childhood epilepsy with centrotemporal spikes (BCECTS)
- early onset benign childhood occipital epilepsy (Panayiotopoulos type)
- late-onset childhood occipital epilepsy (Gastaut type) .
BCECTS or rolandic seizures is the most common manifestation of benign childhood seizures with excellent prognosis and remission within 2–4 years of onset . Onset is from age 1 to 14 years and peak age of 8 or 9 years.The cardinal clinical manifestations of rolandic seizures are infrequent, often single, focal seizures of facial muscles with sensorimotor symptoms , oropharyngolaryngeal manifestations, speech arrest and drooling . BCECTS is a genetic epilepsy with autosomal dominant inheritance . Except the EEG, all paraclinical findings including brain imaging are normal. In inter-ictal EEG , central temporal spikes are the hallmark of BCECTS . In some children with rolandic seizures , particularly if the seizures are infrequent, mild or nocturnal, may be no need for therapy . Carbamazepine is the preferred AED and Levetiracetam seems to be highly effective.
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